ABSTRACT
Introducción. El rotavirus es la causa más frecuente de diarrea grave en los niños. Son pocos los estudios clínicos sobre la relación entre la gastroenteritis por rotavirus y los grupos sanguíneos ABO. Objetivo. La meta de este estudio fue investigar la función de los grupos sanguíneos, en la incidencia de la gastroenteritis por rotavirus y la gravedad de la gastroenteritis. Métodos. Se realizó la investigación retrospectiva de las historias clínicas de los bebés que nacieron en nuestro hospital y a quienes, durante el seguimiento, se les diagnosticó gastroenteritis aguda. Resultados. En el estudio, se incluyeron 219 (36,3%) pacientes rotavirus positivos y 383 (63,6%) pacientes rotavirus negativos. El grupo sanguíneo A se detectó más frecuentemente en el grupo rotavirus positivo que en el grupo rotavirus negativo (50,6% frente a 42,2%, p= 0,047). Las tasas de hospitalización de los casos con gastroenteritis por rotavirus en los niños con el grupo sanguíneo A (30,6% frente a 8%, p < 0,001) fueron significativamente más altas. Conclusiones. Se determinó que la gastroenteritis por rotavirus fue más frecuente en los niños con el grupo sanguíneo A. Se detectó que las tasas de hospitalización de estos pacientes fueron más altas. Por lo tanto, en los niños con el grupo sanguíneo A, podría ser necesario estudiar cuidadosamente la gastroenteritis por rotavirus.
Introduction. Rotavirus is the most common cause of severe diarrhea in children. There is only a few clinical studies about the relationship between rotavirus gastroenteritis and ABO blood groups. Objective. The aim of this study was to investigate the role of blood groups, if any present, in the incidence of rotavirus gastroenteritis, and the severity of the gastroenteritis. Methods. The file records of babies born in our hospital and diagnosed with acute gastroenteritis in their follow up were investigated retrospectively. Results. The study was conducted with 219 (36.3%) rotavirus positive and 383 (63.6%) rotavirus negative patients. The A blood group was detected more commonly in the rotavirus positive group compared to the rotavirus negative group (50.6 vs. 42.2%, p= 0.047). Hospitalization rates of the cases with rotavirus gastroenteritis among children with the A blood group (30.6 vs. 8%, p=Ë0.001) were significantly higher. Conclusions. Rotavirus gastroenteritis was determined to be more common in children with A blood group. The hospitalization rates of such patients were detected to be higher. Therefore, rotavirus gastroenteritis among children with blood group A should be monitored closely.
Subject(s)
Humans , Infant , Child, Preschool , Child , Rotavirus Infections/blood , ABO Blood-Group System , Rotavirus/isolation & purification , Gastroenteritis/blood , Gastroenteritis/virology , Rotavirus Infections/epidemiology , Severity of Illness Index , Incidence , Retrospective Studies , Cohort Studies , Gastroenteritis/epidemiologyABSTRACT
Objective: To determine risk factors and short term outcomes in infants with fetal macrosomia independent of gestational diabetes. Method: Patient records of babies born in Bolu Izzet Baysal Obstetrics-Gynaecology and Paediatrics Hospital between 1st January 2007 and 31st December 2010 with weights of 4000g or more were assessed retrospectively. Data were analysed using SPSS version 17.0. Babies born outside hospital and infants of diabetic mothers were excluded. Control group comprised 500 healthy infants weighing 2500-3999g, born during the same period. Chi-square test, student-t test, Mann-Whitney test and multiple regression analysis were the statistical tests used. Results: Of 10,898 babies delivered in our hospital during the 4 year study period, 509 (4.7%) weighed 4000g or more. Significantly more non-diabetic macrosomic babies were male compared to controls (p<0.001). Significantly more non-diabetic pregnant women older than 35 years delivered macrosomic infants compared to non-diabetic pregnant women 35 years or less (p<0.001). Significantly more non-diabetic pregnant women who delivered macrosomic infants were multipara compared to controls (p<0.001). No significant statistical differences were detected in mode of delivery between cases and controls (p>0.05). The 5th minute Apgar scores in the non-diabetic macrosomic group was significantly lower than in controls (p<0.001). Non-diabetic macrosomic babies had significantly more birth injuries than controls (p=0.009). Risk of developing hypoglycaemia and hypocalcaemia were significantly higher in non-diabetic macrosomic babies compared to controls (p<0.05). Conclusion: In our study the risk factors for non-diabetic fetal macrosomia were advanced age pregnancy, multiparity and male sex.